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研究员

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刘永升

  • 职称：研究员
  • 学科：
  • 电子邮件：liuysh@fjirsm.ac.cn
  • 研究方向：

    稀土生物医学、放射性同位素药物（核药）研发、高性能光电材料与器件研发

简介

刘永升，理学博士、研究员、博士生导师。2001年毕业于山东师范大学化学系，2007和2010年分获中国科学院福建物质结构研究所物理化学专业理学硕士和博士学位。主要从事多功能稀土纳米生物医用材料的肿瘤诊疗一体化应用研究以及高性能光电材料与器件的研发工作，在国内率先开展肿瘤精准诊疗一体α医用同位素放射性药物研发工作。已在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.、Nat. Commun.等刊物发表SCI论文80多篇，论文他引>8500次，H因子42；受理中国发明专利和PCT专利46项、授权21项（含欧盟专利1项），其中18项研发专利以技术转让形式2080万元转让，并获里程碑式后续研发合同5亿元；孵化成立集同位素生产、分离纯化、药物研发和临床应用于一体的高科技公司—中科稀土纳米科技（河北）有限公司；先后主持国家自然科学基金重点/面上/青年项目、中国科学院青促会优秀会员专项以及闽都创新实验自主部署科研项目等研究课题，总经费超6000万元。2010年获中国科学院院长优秀奖、卢嘉锡优秀研究生奖、福建省自然科学论文一等奖。2013年入选中国科学院青促会会员，2017年入选中国科学院青促会优秀会员；2018年入选海西创新研究院“百人计划”；2017年获福建省自然科学二等奖（第二完成人）；2018年获中国稀土科技奖基础研究类一等奖（第二完成人）；2023年入选福建省“CX之星”人才项目，2024年入选福建省高层次“B”类人才。

代表性论著

1. Youchao Wei, Xianjin Wang, Zhaoyu Wang, Di Wang, Yameng Chen, Haoyu Zhang, Yao Zhao, Yongsheng Liu,* Qing Zhao* & Maochun Hong,* Fabricating solid-solution-type perovskite/fluoride nanocomposites through sublattice interlocking for high-performance photovoltaics, Adv. Funct. Mater., 2024, 34, 2316058.

2. Zhifen Wu, Hao Chen, Hongyun Zhang, Lixiang Ye, Yongsheng Liu*, Pengming Sun*, and Maochun Hong*, Construction of Tumor-Cell Nucleus Targeting Lanthanide Nano-Prodrugs with Lutetium-177 Labelling for High-Efficient Fluorescence Tumor-Localization and Radionuclide Therapy, Nano Today, 2024, 55, 102214.

3. Zhaoyu Wang, Youchao Wei,* Yameng Chen, Haoyu Zhang, Jianxi Ke, Yongsheng Liu*, and Maochun Hong, “Whole-Body” Fluorination for Highly Efficient and Ultra-Stable All-Inorganic Halide Perovskite Quantum Dots, Angew. Chem. Int. Ed., 2024, 63, e202315841.

4. Guowei Li, Shihui Jiang, Aijun Liu, Lixiang Ye, Jianxi Ke, Caiping Liu, Lian Chen*, Yongsheng Liu* & Maochun Hong*, “Proof of Crystal-Field-Perturbation-Enhanced Luminescence of Lanthanide-Doped Nanocrystals through Interstitial H+ Doping”, Nature Communications, 2023, 14, 5870.

5. Licheng Yu, Youchao Wei*,Yuanchao Lei, Caiping Liu, Yongsheng Liu,* and Maochun Hong,* Achieving Intrinsic Dual-Band Excitonic Luminescence from a Single 3D Perovskite Nanoparticle through Ni2+-mediated Halide Anion Exchange, CCS Chem., 2023, 5, 1-13.

6. Yameng Chen, Zhaoyu Wang, Youchao Wei,* Yongsheng Liu,* and Maochun Hong*, Exciton Localization for Highly Luminescent Two-Dimensional Tin-Based Hybrid Perovskites through Tin Vacancy Tuning, Angew. Chem. Int. Ed., 2023, 62(18) e202301684.

7. Youchao Wei, Yao Zhao, Caiping Liu, Zhaoyu Wang, Feilong Jiang, Yongsheng Liu,* Qing Zhao,* Dapeng Yu, and Maochun Hong*, “Constructing All-Inorganic Perovskite/Fluoride Nanocomposites for Efficient and Ultra-Stable Perovskite Solar Cells”, Adv. Funct. Mater., 2021, 31, 2106386.

8. Huhui Fu, Rui Feng, Feilong Jiang, Yongsheng Liu*, Maochun Hong*, “Activating Surface Dark-Emitters in Lanthanide-Doped Ultrasmall Nanoparticles for Biological Applications Based on Inter-Particle Energy Transfer”, CCS Chem., 2020, 2, 2155-2163.

9. Huhui Fu, Caiping Liu, Pengfei Peng, Feilong Jiang, Yongsheng Liu,* and Maochun Hong,* “Peasecod-like Hollow Upconversion Nanocrystals with Excellent Optical Thermometric Performance”, Adv. Sci., 2020, 7 (14), 2000731.

10. Pengfei Peng, Na Wu, Lixiang Ye, Feilong Jiang, Wei Feng, Fuyou Li, Yongsheng Liu,* and Maochun Hong,* “Biodegradable Inorganic Upconversion Nanocrystals for In Vivo Applications”, ACS Nano, 2020, 14 (12), 16672-16680.

11. Shenghan Zou, Caiping Liu, Renfu Li, Feilong Jiang, Xueyuan Chen, Yongsheng Liu,* and Maochun Hong,* “From Nonluminescent to Blue-Emitting Cs4PbBr6Nanocrystals: Tailoring the Insulator Bandgap of 0D Perovskite through Sn Cation Doping”, Adv. Mater., 2019, 31 (24), 201900606.

12. Shenghan Zou, Yongsheng Liu,* Jianhai Li, Caiping Liu, Rui Feng, Feilong Jiang, Yongxiang Li, Jizhong Song, Haibo Zeng,* Maochun Hong,* and Xueyuan Chen* “Stabilizing Cesium Lead Halide Perovskite Lattice through Mn (II)-Substitution for Air-Stable Light-Emitting Diodes”, J. Am. Chem. Soc., 2017, 139, 11443-11450.

13. Yongsheng Liu, Datao Tu, Haomiao Zhu, and Xueyuan Chen*, “Lanthanide-Doped Luminescent Nanoprobes: Controlled Synthesis, Optical Spectroscopy, and Bioapplications”, Chem. Soc. Rev. 2013, 42, 6924-6858.

14.  Yongsheng Liu, Shanyong Zhou, Datao Tu, Zhuo Chen, Mingdong Huang, Haomiao Zhu, En Ma, and Xueyuan Chen*, “Amine-Functionalized Lanthanide-Doped Zirconia Nanoparticles: Optical Spectroscopy, Time-Resolved Fluorescence Resonance Energy Transfer Biodetection and Targeted Imaging”, J. Am. Chem. Soc., 2012, 134, 15083-15090.

15. Yongsheng Liu, Datao Tu, Haomiao Zhu, Renfu Li, Wenqin Luo, and Xueyuan Chen*, “A Strategy to Achieve Efficient Dual-Mode Luminescence of Eu3+ in Lanthanides Doped Multifunctional NaGdF4 Nanocrystals”, Adv. Mater., 2010, 22, 3266-3271.