题 目：How plant cryptochromes work

报告人：Chentao Lin　教授

单 位：Plant Proteomics Research Center, Fujian Agriculture and Forestry University

时 间：2025/6/9　09:00

地 点：综合楼三层320报告厅

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附简介：

报告摘要： Plant cryptochromes (CRYs) are photolyase-like blue light receptors that contain FAD chromophore. In plants grown in darkness, CRYs exist as monomers. Photoexcited CRYs oligomerize to form homo-tetramers. CRYs physically interact with non-constitutive or the constitutive CRY-interacting proteins to form the non-constitutive or the constitutive CRY complexes, respectively. The non-constitutive CRY complexes exhibit different affinity to CRYs in response to light, and they act by the light-induced fit (lock-and-key) mechanism. The constitutive CRY complexes exhibit similar affinity to CRYs regardless of light, and they act by the light-induced LLPS (Liquid-Liquid Phase Separation) mechanism. More than 85 CRY-interacting proteins have been reported so far, including transcription factors, chromatin remodelers, splicing factors, 3 ubiquitin ligases, protein kinases, mRNA methyltransferases, light and hormone receptors, and others. These CRY complexes mediate blue-light regulation of transcription, mRNA methylation, mRNA splicing, protein modification, and proteolysis to modulate plant growth and development. 

报告人简介： Prof. Chentao Lin is an internationally recognized plant biologist whose research has significantly advanced the understanding of plant photoreceptors and light-regulated development. He received his B.S. in Agronomy from the South China College of Tropical Crops (1982), M.S. in Botany from Iowa State University (1987), and Ph.D. in Genetics from Michigan State University (1992), followed by postdoctoral training at the University of Pennsylvania as an NIH fellow. In 1996, he joined the University of California, Los Angeles (UCLA), where he served as a faculty member in the Department of Molecular, Cell and Developmental Biology for over 25 years. In 2022, he returned to China as Professor and Director of the Basic Forestry and Proteomics Research Center at Fujian Agriculture and Forestry University. His research focuses on the molecular mechanisms of blue-light perception, cryptochrome signaling, and light-regulated mRNA methylation in plants, with broad implications for plant growth, circadian regulation, and environmental adaptation. Prof. Lin has published over 150 papers in leading scientific journals including Science, Nature Plants, Annual Review of Plant Biology, and Current Biology. His major contributions include the discovery of plant cryptochrome photoreceptors CRY1 and CRY2, and the elucidation of their mechanisms in photoactivation, phosphorylation, degradation, and transcriptional regulation. He is a Fellow of the American Association for the Advancement of Science (AAAS), and an active member of the American Society of Plant Biologists and the International Society of Plant Molecular Biology. He serves on the Faculty of 1000 and has received numerous honors such as the NIH National Research Service Award and the UCLA Career Development Award. Currently supported by major grants from the National Natural Science Foundation of China, Prof. Lin continues to lead cutting-edge research and foster international collaboration in plant molecular biology. 

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